Oxymetazoline Therapeutic Cheat Sheet
OxymetazolineOxymetazoline is an adrenoreceptor agonist which is FDA-approved for dermatologic conditions including persistent facial erythema in rosacea and blepharoptosis. Functioning primarily as a vasoconstrictor with additional anti-inflammatory properties, oxymetazoline targets the sustained vasodilated state of cutaneous blood vessels in rosacea by inducing vasoconstriction and reducing the persistent f …
Bimekizumab-bkzx Therapeutic Cheat Sheet
BIMEKIZUMABBimekizumab (Bimzelx®) is a new injectable medication FDA approved for plaque psoriasis. It is the first and only FDA approved IL-17A and IL-17F inhibitor for this disease, but is also being used as an off-label option for other conditions including psoriatic arthritis and hidradenitis suppurativa. This Therapeutic Cheat Sheet will focus on the on and off label uses of bimekizumab.   Bimekizuma …
Alitretinoin Therapeutic Cheat Sheet
alitretinoinAlitretinoin (9-cis-retinoic acid) is a naturally occurring endogenous retinoid that in gel form is FDA approved for AIDs-related localized cutaneous Kaposi’s sarcoma (KS)1. As compared to other topical retinoids, alitretinoin is unique in that it binds to all known intracellular retinoid receptors (RARs and RXRs), allowing it to exert anti-proliferative and apoptotic effects, particularly usefu …
Tirbanibulin Therapeutic Cheat Sheet
TirbanibulinCurrent field-directed treatments of actinic keratosis (AK), a pre-malignant condition, are often limited by severe local reactions and/or complex treatment. Tirbanibulin, a novel potent anti-proliferative synthetic agent that inhibits tubulin polymerization and Src kinase signalling, offers a convenient, safe, and effective field treatment of actinic keratosis. We continue our surgical Therapeut …
Fluconazole Therapeutic Cheat Sheet
fluconazoleFluconazole is a synthetic triazole with a broader antifungal spectrum than the imidazole class. Resistance to first-pass metabolism and consistent oral absorption are advantages over agents like ketoconazole in the antifungal armamentarium, particularly in the context of the United States Food and Drug Administration’s reinforced warning against oral ketoconazole for skin and nail infections, d …

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