The correct answer is C. K6, K16.
Expression of keratins K6 and K16 is upregulated in hyperprolferative psoriasis plaques. The other listed keratins are not involved in psoriasis.
Nrf2 Promotes Keratinocyte Proliferation in Psoriasis through Up-Regulation of Keratin 6, Keratin 16, and Keratin 17.
Yang L, Fan X, Cui T, Dang E, Wang G.
J Invest Dermatol. 2017 Oct;137(10):2168-2176. [https://www.ncbi.nlm.nih.gov/pubmed/28576737]