The correct answer is A. Type I
Correct Answer Explanation
Type I (familial lipoprotein lipase deficiency or apoprotein CII deficiency) hyperlipoproteinemia has increased chylomicrons as a feature, and presents with eruptive xanthomas and lipemia retinalis. For the other hyperlipoproteinemias, the associated lipid abnormalities are as follows: Type IIa — increased LDL; Type IIb — increased LDL and VLDL; Type III — increased IDL; Type IV — increased VLDL. Type V has increased chylomicrons and increased VLDL.
Incorrect Answer Explanation
Severe hypertriglyceridaemia: Type 1 and V is characterized by:
- Mixed genetic and lifestyle causes
- Diabetes mellitus
- Familial LPL deficiency
- Triglycerides > 10 mmol/L
- Raised total cholesterol
- Raised chylomicrons
- Raised VLDL cholesterol
Book: Textbook of Dermatology. Ed Rook A, Wilkinson DS, Ebling FJB, Champion RH, Burton JL. Fourth edition. Blackwell Scientific Publications. Chapter 92: Xanthomas. William Trent Massengale. Dermatology, 4th edition. Pg. 1634.