Friday Pop Quiz #222

The correct answer is D. Silica.

The image shows a foreign body reaction with sarcoidal granulomas consistent with such a reaction. The presence of colorless, birifrigent crystals is most characteristic of silicosis.

Aluminum and zirconium have no polarizable crystals, while sarcoidosis and gout have different presentations from a foreign body reaction.


Pimentel L, Barnadas M, Vidal D, Sancho F, Fontarnau R, Alomar A. Simultaneous presentation of silicone and silica granuloma: a case report. Dermatology. 2002;205(2):162-165. doi:10.1159/000063897