Tranexamic Acid Therapeutic Cheat Sheet
Tranexamic acid (TXA) is a synthetic lysine derivative that reversibly blocks the lysine-binding site on plasminogen, preventing conversion to plasmin. While originally developed as an antifibrinolytic agent to reduce bleeding, TXA has several downstream effects that make it useful in dermatology, particularly for pigmentary disorders, with emerging evidence in inflammatory disorders as well. TX …
Tranexamic acid (TXA) is a synthetic lysine derivative that reversibly blocks the lysine-binding site on plasminogen, preventing conversion to plasmin. While originally developed as an antifibrinolytic agent to reduce bleeding, TXA has several downstream effects that make it useful in dermatology, particularly for pigmentary disorders, with emerging evidence in inflammatory disorders as well. TX … 
Concerns over the use of AI in dermatology often center on skin tone bias. Machine learning’s data sets commonly reflect the Eurocentric focus that’s traditionally found in dermatologic images. Now researchers are raising awareness of another bias in these data sets: sex and gender differences in the skin. These hormonal and morphologic differences are completely normal. However, when not acco … 
When treating pediatric patients, knowing how to appropriately use topical steroids in this patient population is essential, according to Dr. Karan Lal, a dermatologist in Scottsdale, Ariz. Next Steps in Derm, in partnership with Skin of Color Update, interviewed Dr. Lal, who shares how to taper topical steroids and the role of non-steroidal agents. Hear the latest in the safety profile of topica … 
Bullous diseases, including bullous pemphigoid, may present differently in patients with darker skin tones. Next Steps in Derm, in partnership with Skin of Color Update, interviewed Dr. Prince Adotama, assistant professor at NYU Langone’s Ronald O. Perelman Department of Dermatology. Watch as Dr. Adotama outlines what clinicians need to know about bullous pemphigoid. Learn how the treatment lan … 
Hyperpigmentation often drives dermatology visits for patients with skin of color as an uneven skin tone can be distressing for patients. In fact, in cases where hyperpigmentation is a sequelae of an inflammatory skin condition, the hyperpigmentation can be more concerning for patients than the skin condition that caused it. Globally and in the U.S., this distress can lead patients to self-treat w …