Derm In-Review

Infantile Rash – Friday Pop Quiz 6/18
by NEXT STEPS IN DERM TEAM on
The dermatologist on call is requested to visit the NICU to evaluate an infant born 12 hours earlier with a disseminated rash. Two punch biopsies are performed and a c-KIT positive infiltrate is noted in the dermis of each sample. What is the most likely diagnosis? A. T cell lymphoma B. Mastocytosis C. Syphilis, congenital D. B cell lymphoma E. Neuroblastoma To find out the co …

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It’s Mnemonic Monday! Stains for Mast Cells
stains for mast cells
by NEXT STEPS IN DERM TEAM on
On this Mnemonic Monday, we challenge you to remember stains for Mast cells. "GIMME TO YOUR LEDER" Giemsa Toluidine blue Leder Remember  "rub me and take me to your Leder" as a mnemonic to remember that Leder stain still works after Darier's sign is induced (after de-granulation of mast cells). Side note: Not all stains are included here. Ex: tryptase and c-kit would also stain mast …

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Pigmented Lesion – Friday Pop Quiz 6/11
by NEXT STEPS IN DERM TEAM on
This patient presented for a different lesion but you see this during your exam and perform a biopsy. If the pigmented lesion seen here is 0.9mm deep, what is the recommended margin for excision? A. <0.5cm B. 0.5cm C. 1.0cm D. 2.0cm E. >2.0cm To find out the correct answer and read the explanation, click here.  Brought to you by our brand partner Derm In-Review.  A …

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Pruritic Rash – Friday Pop Quiz 6/4
pruritic rash
by NEXT STEPS IN DERM TEAM on
This healthy 2-year-old female presents with a 2-day history of the pruritic rash seen here. She had mild edema of the dorsal hands and feet and positive dermatographism on exam. All lesions were transient, lasting less than 24 hours in the same location. She was otherwise well and her parents denied any fever or systemic symptoms. What is the best diagnosis? A. Serum sickness-like reaction …

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It’s Mnemonic Monday! Extramammary Paget’s Disease
Extramammary Paget’s disease immunohistochemical markers
by Jacqueline McKesey, MD MS on
On this Mnemonic Monday, we challenge you to remember immunohistochemical markers for paget cells in Extramammary Paget’s Disease with the following mnemonic: "EXTRA GROSS LOVE PASSES CANCER" Extra- Extramammary Paget’s Disease Gross- Gross cystic disease fluid protein 15 (GCDFP-15) LOVE- Low molecular weight cytokeratins PASses- Period acid-Schiff (PAS) CANCER- CEA The wo …

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