Correct Answer: B. Collagen VII
Explanation: Bart’s syndrome refers to congenital aplasia cutis (typically of the shins) and associated epidermolysis bullosa, most commonly dominant dystrophic EB. In dominant dystrophic EB there is a defect in Collagen VII.
Reference: Zelickson B, Matsumura K, Kist D, et al. Bart’s Syndrome Ultrastructure and Genetic Linkage. Arch Dermatol. 1995;131(6):663-668.