It’s Pop Quiz Friday 7/13! Let’s see if you get it right!
An 80-year-old man with Parkinson’s disease developed a new pruritic eruption with these cutaneous findings. What is the antigenic target of the autoantibodies generated in this condition
A. NC16A of BPAg1
B. NC16A of BPAg2
C. C-terminal of BPAg1
D. C-terminal of BPAg2
E. alpha-6-beta-4 integrin
To find out the correct answer and read t …
An 80-year-old man with Parkinson’s disease developed a new pruritic eruption with these cutaneous findings. What is the antigenic target of the autoantibodies generated in this condition
A. NC16A of BPAg1
B. NC16A of BPAg2
C. C-terminal of BPAg1
D. C-terminal of BPAg2
E. alpha-6-beta-4 integrin
To find out the correct answer and read t … Continue reading "It’s Pop Quiz Friday 7/13! Let’s see if you get it right!"
This patient is not a candidate for systemic therapy and declines surgical treatment. Which of the following injectable agents is an oncolytic virus that is FDA-approved for inoperable disease?
A) Talimogene laherparepvec (T-VEC)
B) Interleukin-2
C) GM-CSF
D) Rose bengal
E) bacille Calmette-Guerin (BCG)
To find out the correct answer and … 
Which dermoscopic features are illustrated here?
A) Reticular pattern and milky-red globules
B) Atypical pigment network & blue-white veil
C) Globular pattern & radial streaks
D) Homogenous pattern & pseudopoding
E) Starburst pattern & regression
To find out the correct answer and read the explanation, click here.
… 
What is the next step when seeing this patient?
A) No further work up needed
B) Endoscopy to look for vascular malformations w/ potential GI bleeding
C) Careful follow up to monitor for malignant transformation, including possible imaging and biopsy in the future.
To find out the correct answer and read the explanation, click here.
Question pro … 
Connective tissue diseases are a boards favorite, and lab interpretation, including identifying ANA patterns from photos, are fair game. I’ve put together the following table of ANA patterns as well as their associated disease states and autoantibodies for easy memorization (and easy points!).
Image sources:
Centromere: https://www.researchgate.net/figure/Centromere-staining_fig9_452 … 