Diabetes – Friday Pop Quiz 4/28/2023
You are asked to evaluate this 44 year old man with a history of diabetes and housing insecurity who is currently in the emergency room. He is also on metformin. The area is exquisitely tender. What is the best first step in your work-up?
A. Deep punch biopsy (double-punch) to evaluate subcutaneous tissue
B. Bacterial and fungal swab
C. Imaging and surgical consult
D. Oral doxycycl …
You are asked to evaluate this 44 year old man with a history of diabetes and housing insecurity who is currently in the emergency room. He is also on metformin. The area is exquisitely tender. What is the best first step in your work-up?
A. Deep punch biopsy (double-punch) to evaluate subcutaneous tissue
B. Bacterial and fungal swab
C. Imaging and surgical consult
D. Oral doxycycl … 
A 15-year-old girl comes to the clinic with her mother for dry, itchy skin that waxes and wanes for years. The patient states it worsens in the dry winter, along with during times of stress and anxiety. Examination reveals the findings pictured. What is the function of the gene product most commonly mutated in for this condition?
A. Initiate and maintain intercellular adhesion of keratinocy … 
A 48-year-old man is admitted for fever and malaise and is treated with antibiotics. Approximately 10 days after initiation of antibiotics, the patient’s skin, including the mucous membranes, blisters and desquamates, as shown. Which of the following laboratory findings is most likely to prognosticate the patient’s mortality?
A. Body surface area involvement
B. Heart rate
C. Serum … 
Which of the following cell types is most likely to be found on a Wright-Giemsa stain of fluid from the lesions shown on this 2-day-old child?
A. Basophils
B. Eosinophils
C. Histiocytes
D. Mast cells
E. Neutrophils
To find out the correct answer and read the explanation, click here.
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A 55-year-old patient from the Caribbean presents with indurated scaly papules and plaques on his trunk, arms, and legs. The rash started six months ago and has progressed rather quickly. Review of system was notable for pruritus and xerosis; patient reported no personal history of skin diseases, including psoriasis and atopic dermatitis. Several 4-mm punch biopsies were performed. Based on th … 