Cyclophosphamide Therapeutic Cheat Sheet
Cyclophosphamide, an alkylating agent introduced in the 1950s, has long served as a cornerstone therapy in rheumatology and oncology for its potent cytotoxic and immunosuppressive effects. In dermatology, it has been employed as a rescue agent for severe, refractory autoimmune and inflammatory skin diseases, particularly those associated with systemic connective tissue disorders. Its role spans co …
Cyclophosphamide, an alkylating agent introduced in the 1950s, has long served as a cornerstone therapy in rheumatology and oncology for its potent cytotoxic and immunosuppressive effects. In dermatology, it has been employed as a rescue agent for severe, refractory autoimmune and inflammatory skin diseases, particularly those associated with systemic connective tissue disorders. Its role spans co …
In the age of immunotherapy, is there a place for hedgehog inhibitors in cutaneous oncology?
ODAC Guest Advisor Dr. Vishal Patel says hedgehog inhibitors are even more important now. Dr. Patel spoke with Next Steps in Derm, in partnership with the ODAC Dermatology Conference, where he outlined scenarios in clinical treatment where hedgehog inhibitors make sense. Learn about the two approved m …
Seborrheic dermatitis, a common but often overlooked condition, has received little attention in recent decades despite its significant impact on patients, including itch and cosmetic concerns. At the 2024 Skin of Color Update, Dr. Shawn Kwatra, Professor and Chair of Dermatology at the University of Maryland School of Medicine, provided a fresh perspective on its evaluation and management in pati …
Dermatologists know how to perform hidradenitis suppurativa deroofing – they just don’t know that they know how! That’s according to Dr. Steven Daveluy, professor and program director at Wayne State Dermatology. In an interview with Next Steps in Derm, in partnership with the ODAC Dermatology Conference, Dr. Daveluy shares his encouragement for dermatologists to try deroofing even if they we …
Forbes profiled the skincare ingredient bisabolol, which is making headlines for its anti-inflammatory properties. Commonly used in skincare products as alpha-bisabolol, an extract from the essential oils of the German chamomile and Brazilian candei tree, bisabolol is an antioxidant with anti-microbial properties. Dermatologist Dr. Hallie McDonald says bisabolol also enhances the effects of other …