Afamelanotide Therapeutic Cheat Sheet
Photosensitive skin conditions can result in cutaneous and systemic symptoms that can have a marked effect on quality of life due to ubiquitous UV exposure. Erythropoietic protoporphyria, for example, can cause severe photodermatitis, excruciating burning and neuropathic pain, nausea, and deep-rooted fear of sunlight that leads to debilitating lifestyle modifications such as remaining indoors. We …
Colchicine Therapeutic Cheat Sheet
Colchicine, a microtubule polymerization inhibitor, was first described for use in treating joint pain and swelling in ancient Egypt and has since become a mainstay in the medical management of gout. Beyond its indicated uses, it has numerous off-label dermatologic applications, particularly for neutrophilic and autoimmune conditions. As a potent anti-inflammatory, colchicine requires careful lab …
Oral Ivermectin Therapeutic Cheat Sheet
Oral IvermectinIvermectin is a semi-synthetic derivative of avermectins, a class of macrocyclic lactones with broad-spectrum anti-parasitic effects. Its unique mechanism of action, favorable safety profile, and anti-inflammatory properties make ivermectin invaluable in the treatment of a wide range of cutaneous parasitic infestations, including scabies. We continue our series, Therapeutic Cheat Sheet, with a cl …
Oral Ivermectin
Nemolizumab Therapeutic Cheat Sheet
NemolizumabAtopic dermatitis and prurigo nodularis are chronic, life-altering diseases with a common feature of debilitating pruritus that significantly impacts our patients’ qualities of life. For those with resistant and extensive disease, dermatologists now have nemolizumab in our armamentarium, the first FDA approved IL-31 inhibitor. We continue our series, Therapeutic Cheat Sheet, with a closer look a …
Nemolizumab
Permethrin Therapeutic Cheat Sheet
PermethrinPermethrin is a synthetic neurotoxic pyrethroid derived from chrysanthemums with significant dermatologic value for its powerful insecticide properties when used topically. We continue our series, Therapeutic Cheat Sheet, with a closer look at permethrin, which is FDA-approved for the treatment of scabies and pediculosis capitis infestations. Permethrin Therapeutic Cheat Sheet Compiled by: Dillo …
Permethrin