Tirbanibulin Therapeutic Cheat Sheet
Current field-directed treatments of actinic keratosis (AK), a pre-malignant condition, are often limited by severe local reactions and/or complex treatment. Tirbanibulin, a novel potent anti-proliferative synthetic agent that inhibits tubulin polymerization and Src kinase signalling, offers a convenient, safe, and effective field treatment of actinic keratosis. We continue our surgical Therapeut …
Current field-directed treatments of actinic keratosis (AK), a pre-malignant condition, are often limited by severe local reactions and/or complex treatment. Tirbanibulin, a novel potent anti-proliferative synthetic agent that inhibits tubulin polymerization and Src kinase signalling, offers a convenient, safe, and effective field treatment of actinic keratosis. We continue our surgical Therapeut … 
Fluconazole is a synthetic triazole with a broader antifungal spectrum than the imidazole class. Resistance to first-pass metabolism and consistent oral absorption are advantages over agents like ketoconazole in the antifungal armamentarium, particularly in the context of the United States Food and Drug Administration’s reinforced warning against oral ketoconazole for skin and nail infections, d … 
The use of antimicrobial therapy in the field of cutaneous surgery can be a difficult and controversial topic. Overall, there are a lack of randomized controlled clinical trials evaluating the efficacy of antimicrobial prophylaxis within our field. As a result, much of the recommendations for antimicrobial prophylaxis are extrapolated from other fields, such as dentistry, cardiology, and orthopedi … 
Ruxolitinib (OPZELURA) is a twice daily topical cream that is FDA approved for non-segmental vitiligo and mild to moderate atopic dermatitis1. JAK inhibitors are a class of drugs effective in treating a wide variety of inflammatory conditions. Initially only FDA approved for non-dermatologic conditions such as rheumatoid arthritis and ulcerative colitis, there is now strong evidence that JAK/STAT … 
Following numerous office-based dermatologic procedures, erythema, swelling, and scarring are often feared complications experienced by our patients. Understanding the wound healing response is synonymous with understanding the stages of healing and ultimately the clinical appearance of each wound. Possessing and sharing a firm grasp on this knowledge allows for patient empowerment during the woun … 