Intravenous Immune Globulin (IVIG) Therapeutic Cheat Sheet
Intravenous Immune Globulin (IVIG)
by Nidhi Shah, MD on
Intravenous immune globulin (IVIG) is a concentrate of pooled immunoglobulins derived from plasma donors. Its unique mechanism of action expands the utility of the medication to a variety of conditions. We continue our series, Therapeutic Cheat Sheet, with a closer look at IVIG, which is FDA-approved for the treatment of dermatologic conditions including dermatomyositis, Kawasaki disease, ITP, and …
DaxibotulinumtoxinA Therapeutic Cheat Sheet
by Alexis Carrington, MD on
Neurotoxins are the mainstay for multiple aesthetic and medical treatments. They are safe and effective treatment for rhytides, but are also temporary, requiring repeat injections about every 3-4 months.1,2 Now, a recently approved formulation of neurotoxin is fulfilling some patient’s desire for a longer lasting effect. Injection of daxibotulinumtoxinA is FDA-approved for treatment of moderate …
Rituximab Therapeutic Cheat Sheet
by Emily Murphy, MD on
Rituximab was the first monoclonal antibody approved for cancer treatment and now in dermatology, this medication has been life-altering for patients with the severe, autoimmune blistering disease, pemphigus vulgaris. We continue our series, Therapeutic Cheat Sheet, with a closer look at rituximab, which is FDA-approved for the treatment of pemphigus vulgaris, and is also used off label for other …
Baricitinib Therapeutic Cheat Sheet
by Alexis Carrington, MD on
Baricitinib (Olumiant®) is a once daily oral medication recently FDA approved for severe alopecia areata, which is defined as having a Severity of Alopecia Tool (SALT) score of 50 or higher.1 JAK inhibitors are a relatively new class of drug demonstrating efficacy and safety in a range of inflammatory skin disorders. Emerging studies have highlighted baricitinib’s effectiveness for conditions l …
Roflumilast Therapeutic Cheat Sheet
by Adam Rosenfeld, MD on
Roflumilast is a non-steroidal topical cream that was FDA approved for the treatment of plaque psoriasis in 2022.1 Roflumilast selectively inhibits phosphodiesterase-4 (PDE-4), which is an enzyme that mediates inflammatory responses and has been shown to play a role in several dermatologic diseases.2 Prior to topical roflumilast, oral PDE-4 inhibitors have been investigated across a wide variety o …