JDD Corner

Rituximab-Induced Alopecia Universalis in a Patient With Bullous Pemphigoid
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Alopecia areata is a CD8+ T-lymphocyte driven autoimmune disorder leading to reversible hair loss. While most commonly presenting as isolated well-demarcated non-cicatricial alopecic patches on the scalp, subtypes of alopecia areata include alopecia totalis with loss of all scalp hair and alopecia universalis with complete loss of all body hair. Although primarily an idiopathic condition, several …

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Dermal Hypersensitivity Reaction to Semaglutide: Two Case Reports
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Semaglutide is a glucagon-like peptide-1 (GLP-1) analog that was FDA-approved in 2017 for treatment of type II diabetes and in 2021 for treatment for chronic weight management in adults with obesity or overweight with at least one weight-related condition.1 Due to its longer duration of action, it is typically administered subcutaneously once weekly. The safety profile of semaglutide is similar to …

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JDD May 2023 Issue Highlights | Special Focus: Skin Cancer
skin cancer
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The May issue of the Journal of Drugs in Dermatology (JDD) focuses on skin cancer and includes the perfect blend of original articles and case reports. Topics include actinic keratosis versus squamous cell carcinoma, the utility of gene expression profiling in skin cancer, the prevalence of sunscreen use, and many more.  Check out this month’s issue highlights straight from the JDD Editor’s …

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Acute Onset Linear Lichen Planus Pigmentosus of the Forehead: A Case Series
LPP
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INTRODUCTION Linear lichen planus pigmentosus (LPP) of the face is a rare acquired variant of lichen planus, with only a few cases published in the literature.1 It is an inflammatory condition with unknown etiology, characterized by blue-gray hyperpigmented macules, and tends to affect sun-exposed areas of the head and neck.1-4 The pathophysiology of linear LPP is poorly understood, though …

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Graham-Little-Piccardi-Lasseur Syndrome: A Case Report
alopecia
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INTRODUCTION Graham-Little-Piccardi-Lasseur Syndrome (GLPLS) is a rare clinical subtype of lichen planopilaris (LPP) that manifests as a triad of scarring alopecia of the scalp, nonscarring alopecia of the axillary and the pubic skin, and widespread lichenoid follicular papules.1 GLPLS more commonly affects women (male-to-female ratio ≃ 1:4), with the classic patient being a middle-aged Ca …

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