Dermal Hypersensitivity Reaction to Semaglutide: Two Case Reports
semaglutideSemaglutide is a glucagon-like peptide-1 (GLP-1) analog that was FDA-approved in 2017 for treatment of type II diabetes and in 2021 for treatment for chronic weight management in adults with obesity or overweight with at least one weight-related condition.1 Due to its longer duration of action, it is typically administered subcutaneously once weekly. The safety profile of semaglutide is similar to …
semaglutide
A Pearl for Pretibial and Forearm Repair Following Mohs Micrographic Surgery
wound closure Wound repair of the pretibial and forearm regions presents a challenge during dermatologic surgery as these areas are under significant tension and exhibit increased skin fragility. Various methodologies have been proposed for the closure and repair of such wounds, however, the use of the bilayered suture technique may be simpler and more effective than other techniques such as the pinch stitc …
wound closure
Treatment of Advanced Basal Cell Carcinoma With Involvement of the Left Orbit
basal cell carcinomaINTRODUCTION Periocular basal cell carcinoma (BCC) is the most common eyelid malignancy concomitant with ocular morbidity and quality of life impact.1,2 Orbital invasion occurs in 2% of cases and poses challenges for management.1,3 JDD authors highlight a multidisciplinary approach to the treatment of advanced periocular BCC.   CASE JDD authors discuss a 56-year-old male who presente …
basal cell carcinoma
Urticaria Pigmentosa Without Pruritus | Case Report
urticaria pigmentosa Mastocytosis is a group of disorders characterized by the pathologic accumulation of mast cells in various tissues. One example of mastocytosis is urticaria pigmentosa, which presents with mastocytomas that can cause hives and, when irritated, pruritus. To the authors' knowledge, they are describing the first case of urticaria pigmentosa without pruritus. The patient had a positive Darier' …
urticaria pigmentosa
Ruxolitinib 1.5% Topical Cream for the Treatment of Pediatric Alopecia Areata | Case Report
pediatric alopeciaAlopecia areata (AA) is a common autoimmune disorder. Although its pathogenesis is not fully understood, AA involves CD8 T cell-mediated destruction of the hair follicle. Several treatment options exist; however, there is minimal evidence in the pediatric population. Currently, there are no curative treatments for AA. The literature suggests that Janus kinase (JAK) inhibitors may be an effective t …
pediatric alopecia