The correct answer is B. Pseudotumor cerebri.

Both isotretinoin and tetracycline are known to cause pseudotumor cerebri. In combination, the risk is significantly elevated. Symptoms of pseudotumor cerebri include headaches, pulsatile tinnitus, diplopia, and blurred vision. Co-administration of isotretinoin and doxycycline does not increase the risk of the remaining answer choices.

References:

PMID: 27786584