Management of Hailey-Hailey Disease With Ruxolitinib 1.5% Cream
Introduction
Benign Familial Pemphigus (Hailey-Hailey Disease [HHD]) is caused by a mutation within ATP2C1, the gene encoding the calcium pump of golgi apparatuses, impacting keratinocytes' ability to adhere to each other, resulting in acantholysis.1 Clinical presentation of HHD encompasses blisters that become erythematous plaques and fissures within flexural areas on a relapsing basis …
Introduction
Benign Familial Pemphigus (Hailey-Hailey Disease [HHD]) is caused by a mutation within ATP2C1, the gene encoding the calcium pump of golgi apparatuses, impacting keratinocytes' ability to adhere to each other, resulting in acantholysis.1 Clinical presentation of HHD encompasses blisters that become erythematous plaques and fissures within flexural areas on a relapsing basis … Continue reading "Management of Hailey-Hailey Disease With Ruxolitinib 1.5% Cream"
Dr. Robyn Siperstein, a dermatologist in Boca Raton and Boynton Beach, Fla., says don’t limit energy-based devices to cosmetic dermatology. Next Steps in Derm, in partnership with the ODAC Dermatology Conference, interviewed Dr. Siperstein. Watch as she shares three medical conditions where she’s found success using devices originally developed for cosmetic use. Learn why microneedling with ra … 
Patients with hidradenitis suppurativa (HS) are commonly told to eat healthy to improve their disease severity. However, with so many dietary options in this day and age, what does an HS-friendly diet even look like? An article in the November Journal of Drugs in Dermatology shares research analyzing several diets and their impact on HS disease severity, as well as the impact of vitamin and minera … 
A 40-year-old female presents for a scalp biopsy. On histology, you note premature desquamation of the inner root sheath, eccentric epithelial atrophy with hair shafts in close proximity to the dermis, and concentric lamellar fibroplasia of some follicles. There is variably dense lymphocytic perifollicular inflammation, primarily at the level of the upper isthmus and lower infundibulum. There … 
Since skin cancer is a global epidemic, Dr. C. William Hanke, a dermatologic surgeon in Indianapolis, says it’s time to start tapping into the procedural tool box to focus on prevention. Next Steps in Derm, in partnership with the ODAC Dermatology Conference, interviewed Dr. Hanke, who outlines therapies to reverse sun damage that vary in their aggressiveness. Watch as Dr. Hanke shares which pat …