Spesolimab Therapeutic Cheat Sheet
Generalized pustular psoriasis (GPP) is a rare, autoinflammatory condition, with acute, severe flares of diffuse sterile pustules and systemic symptoms that can be life-threatening. Historically, cyclosporine, methotrexate, retinoids, and biologics modulating the interleukin-17 (IL-17), IL-23, and tumor necrosis factor α pathways have been used off-label for management.1 Aberrant IL-36 signaling …
Generalized pustular psoriasis (GPP) is a rare, autoinflammatory condition, with acute, severe flares of diffuse sterile pustules and systemic symptoms that can be life-threatening. Historically, cyclosporine, methotrexate, retinoids, and biologics modulating the interleukin-17 (IL-17), IL-23, and tumor necrosis factor α pathways have been used off-label for management.1 Aberrant IL-36 signaling … 
A laboratory’s recent claim that it detected the carcinogen benzene in certain acne treatments made news recently. The lab, Valisure, filed a petition with the FDA asking for a recall of the products involved. Chemists quoted in an Allure article said the issue is not one of contamination but potentially one of decomposition. The lab says it detected benzene when the benzoyl peroxide products we … 
The neoplasm shown is made of cells that are most likely to contain which of the following substances?
A. Histamine
B. Antibodies
C. Major basic protein
D. Melanin
E. Myeloperoxidases
To find out the correct answer and read the explanation, click here.
… 
Dr. Adam Friedman's lecture at 2024 ODAC conference provided invaluable insights into the nuanced approach required when dealing with patients presenting with alopecia. Addressing the diverse array of alopecia types and their myriad presentations, Dr. Friedman emphasized the significance of a comprehensive clinical history and evaluation to formulate an effective treatment plan. By employing a cas … 
Introducing the April 2024 Editorial Highlights from the Journal of Drugs in Dermatology! This month's issue is packed with groundbreaking research and insights into dermatologic treatments and practices. From original articles exploring innovative therapies for conditions like photoaging and acne vulgaris to case reports shedding light on rare dermatologic phenomena, this issue offers a comprehen …