Afamelanotide Therapeutic Cheat Sheet
Photosensitive skin conditions can result in cutaneous and systemic symptoms that can have a marked effect on quality of life due to ubiquitous UV exposure. Erythropoietic protoporphyria, for example, can cause severe photodermatitis, excruciating burning and neuropathic pain, nausea, and deep-rooted fear of sunlight that leads to debilitating lifestyle modifications such as remaining indoors. We …
Photosensitive skin conditions can result in cutaneous and systemic symptoms that can have a marked effect on quality of life due to ubiquitous UV exposure. Erythropoietic protoporphyria, for example, can cause severe photodermatitis, excruciating burning and neuropathic pain, nausea, and deep-rooted fear of sunlight that leads to debilitating lifestyle modifications such as remaining indoors. We … 
At the 2025 ODAC Dermatology Conference, expert dermatologist Anthony Fernandez, MD, PhD presented a masterful talk on Advances in Psoriasis Treatment: Emerging Therapies and Future Directions. He explored emerging therapies and future directions in psoriasis management. Since 2004, the FDA has approved 14 novel systemic agents to treat moderate to severe psoriasis, 12 of which are biologics, an … 
Colchicine, a microtubule polymerization inhibitor, was first described for use in treating joint pain and swelling in ancient Egypt and has since become a mainstay in the medical management of gout. Beyond its indicated uses, it has numerous off-label dermatologic applications, particularly for neutrophilic and autoimmune conditions. As a potent anti-inflammatory, colchicine requires careful lab … 
At the 2025 ODAC Dermatology conference, Dr. Anthony Fernandez, MD, PhD gave an informative presentation titled, No-Brainer Approaches to Neutrophilic Dermatoses. His presentation focused on discussing the clinical presentation, differential diagnosis considerations, and treatment options of pyoderma gangrenosum and Sweet syndrome.
Pyoderma Gangrenosum (PG)
Pyoderma gangrenosum typically present … 