Ruxolitinib 1.5% Topical Cream for the Treatment of Pediatric Alopecia Areata | Case Report
pediatric alopeciaAlopecia areata (AA) is a common autoimmune disorder. Although its pathogenesis is not fully understood, AA involves CD8 T cell-mediated destruction of the hair follicle. Several treatment options exist; however, there is minimal evidence in the pediatric population. Currently, there are no curative treatments for AA. The literature suggests that Janus kinase (JAK) inhibitors may be an effective t …
pediatric alopecia
JDD June 2024 Issue Highlights
acneIn this June edition of the Journal of Drugs in Dermatology (JDD), we're excited to showcase a selection of groundbreaking research and expert insights that delve into the latest advancements and treatments in dermatology. From innovative acne scar therapies to in-depth analyses of topical acne treatments, this month's featured articles  provide a comprehensive overview of current dermatological …
acne
Sonidegib Therapeutic Cheat Sheet
SonidegibBasal cell carcinoma (BCC) is the most common human cancer. When curative surgery and radiotherapy are contraindicated, systemic agents targeting the hedgehog signaling pathway are invaluable options for this subset of adult patients with locally advanced BCC (laBCC). Vismodegib and sonidegib are oral options with similar efficacy and side effect profiles. With the absence of head-to-head comparis …
Sonidegib
Friday pop Quiz #272
The correct answer is C. Gorlin syndrome. The image shows a basal cell carcinoma. One genodermatosis associated with numerous BCCs is Gorlin syndrome/basal cell nevus syndrome. It is due to a mutation in PTCH gene. Patients with Gorlin syndrome can display: Odontogenic keratocysts of the jaw, palmoplantar pits, calcification of the falx cerebri, and skeletal abnormalities. In addition to BC …
Patient Buzz Series: Armpit Detox
armpit detoxYour patients may start asking you if their armpits need some TLC. The latest viral trend as noted by FIRST for Women is an armpit detox. The goal is to address odor, texture and discoloration issues in an area of the body that’s usually covered by products -- antiperspirants or deodorants. Dermatologist Dr. Hadley King says the detox may be helpful when transitioning to a different antiperspira …
armpit detox
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