The correct answer is C. K6, K16.

Expression of keratins K6 and K16 is upregulated in hyperprolferative psoriasis plaques. The other listed keratins are not involved in psoriasis.

Reference:

Nrf2 Promotes Keratinocyte Proliferation in Psoriasis through Up-Regulation of Keratin 6, Keratin 16, and Keratin 17.
Yang L, Fan X, Cui T, Dang E, Wang G.
J Invest Dermatol. 2017 Oct;137(10):2168-2176. [https://www.ncbi.nlm.nih.gov/pubmed/28576737]

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