Ritlecitinib Therapeutic Cheat Sheet
Alopecia areata (AA) is a nonscarring alopecia driven by autoreactive cytotoxic CD8 T cells against hair follicle antigens. With an unpredictable clinical course, which can include alopecia totalis and universalis, AA can be debilitating to patients’ quality of life. Historically, glucocorticosteroids, cyclosporine, methotrexate, and azathioprine were used off-label for non-targeted immunosuppre …
Alopecia areata (AA) is a nonscarring alopecia driven by autoreactive cytotoxic CD8 T cells against hair follicle antigens. With an unpredictable clinical course, which can include alopecia totalis and universalis, AA can be debilitating to patients’ quality of life. Historically, glucocorticosteroids, cyclosporine, methotrexate, and azathioprine were used off-label for non-targeted immunosuppre … 
Alopecia areata (AA) is a common autoimmune disorder. Although its pathogenesis is not fully understood, AA involves CD8 T cell-mediated destruction of the hair follicle. Several treatment options exist; however, there is minimal evidence in the pediatric population. Currently, there are no curative treatments for AA. The literature suggests that Janus kinase (JAK) inhibitors may be an effective t … 
Next Steps in Derm, in partnership with Skin of Color Update, interviewed Dr. Shilpi Khetarpal, dermatologist at the Cleveland Clinic. Watch as Dr. Khetarpal outlines the four categories of adjunctive therapies for hair loss and why clinicians should pair them with traditional medical treatments. Learn Dr. Khetarpal’s typical treatment regimen when using PRP in hair loss patients. Find out what … 
JDD authors Hannah Polster MD, Karen Kagha MD, and Janiene Luke MD report a case of platelet rich plasma for the treatment of scarring alopecia due to discoid lupus erythematosus.
Platelet-rich plasma (PRP) is an autologous concentration of plasma from a patient's blood containing platelets up to 7 times higher than normal plasma.1 Originally indicated to improve connective tissue regeneratio … 