Tranexamic Acid Therapeutic Cheat Sheet
Tranexamic acid (TXA) is a synthetic lysine derivative that reversibly blocks the lysine-binding site on plasminogen, preventing conversion to plasmin. While originally developed as an antifibrinolytic agent to reduce bleeding, TXA has several downstream effects that make it useful in dermatology, particularly for pigmentary disorders, with emerging evidence in inflammatory disorders as well. TX …
Tranexamic acid (TXA) is a synthetic lysine derivative that reversibly blocks the lysine-binding site on plasminogen, preventing conversion to plasmin. While originally developed as an antifibrinolytic agent to reduce bleeding, TXA has several downstream effects that make it useful in dermatology, particularly for pigmentary disorders, with emerging evidence in inflammatory disorders as well. TX … 
Difficult conversations are a routine part of dermatology. They are especially tricky in our specialty because of the time pressure in a full clinic (often 30+ patients a day) and the visual, often deeply personal, nature of skin disease. Medical school teaches universal communication techniques, such as active listening, teach-back, agenda setting, and shared decision-making, that are necessary t … 
Bullous diseases, including bullous pemphigoid, may present differently in patients with darker skin tones. Next Steps in Derm, in partnership with Skin of Color Update, interviewed Dr. Prince Adotama, assistant professor at NYU Langone’s Ronald O. Perelman Department of Dermatology. Watch as Dr. Adotama outlines what clinicians need to know about bullous pemphigoid. Learn how the treatment lan … 
Hyperpigmentation often drives dermatology visits for patients with skin of color as an uneven skin tone can be distressing for patients. In fact, in cases where hyperpigmentation is a sequelae of an inflammatory skin condition, the hyperpigmentation can be more concerning for patients than the skin condition that caused it. Globally and in the U.S., this distress can lead patients to self-treat w … 
Intense itch is a common feature of prurigo nodularis. Why is this the case? Next Steps in Derm, in partnership with Skin of Color Update, interviewed Dr. Raj J. Chovatiya, associate professor at Rosalind Franklin University of Medicine and Science Chicago Medical School. Dr. Chovatiya, who has a PhD in immunology, outlines the science behind the “unbreakable loop” of chronic itch in prurigo …