Friday Pop Quiz 11/7/2025
A 2-year-old male with recurrent flares of the pictured findings developed non-tender nodules on his bilateral thighs. What would likely establish the diagnosis?
A. Genetic testing for STAT3 and DOCK8 mutations
B. Genetic testing for SPINK5 mutations
C. Obtaining immunoglobulin E levels
D. Obtaining serum zinc levels
E. Flow cytometry to evaluate CD18 expression
To find out the …
A 2-year-old male with recurrent flares of the pictured findings developed non-tender nodules on his bilateral thighs. What would likely establish the diagnosis?
A. Genetic testing for STAT3 and DOCK8 mutations
B. Genetic testing for SPINK5 mutations
C. Obtaining immunoglobulin E levels
D. Obtaining serum zinc levels
E. Flow cytometry to evaluate CD18 expression
To find out the … 
An 8-month-old boy is brought in by his mother for concerns of a rash that comes and goes for the last few months, primarily on his face and belly. His older brother suffers from asthma and often has a similar rash on the inside of his elbow and behind his knees. Lead-in Question: The gene most commonly mutated in the photograph is also mutated in which of the following?
A. Palmoplantar ker … 
HealthCentral recently highlighted new research out of Harvard Medical School on the role of Staphylococcus aureus (S. aureus) in itch. Researchers found S. aureus can trigger itch in mice and human cells through communication with sensory neurons.
For an expert’s take, I reached out to Gil Yosipovitch, MD, professor, Stiefel Chair of Medical Dermatology and director of the Miami Itch Center … 
TikTok influencers are recommending a drawing salve as an acne spot treatment. Pain Relief & Instant Drawing Salve (PRID) purports to be a homeopathic way to draw out foreign bodies and relieve the effects of minor skin concerns.
Yet dermatologists in an Allure article about the trend say they do not tell patients to use PRID as an acne spot treatment due to risks of irritation, hyperpigmen … 
It’s an exciting time for new therapies in atopic dermatitis with several therapies recently approved or in late-stage development. Next Steps in Derm, in partnership with ODAC Dermatology, Aesthetic & Surgical Conference, interviewed Baltimore dermatologist Dr. Shawn Kwatra, who outlined the new treatment options. From therapies that target IL-13 and IL-31 to JAK inhibitors, dermatology cl …