Management of Hailey-Hailey Disease With Ruxolitinib 1.5% Cream
Introduction
Benign Familial Pemphigus (Hailey-Hailey Disease [HHD]) is caused by a mutation within ATP2C1, the gene encoding the calcium pump of golgi apparatuses, impacting keratinocytes' ability to adhere to each other, resulting in acantholysis.1 Clinical presentation of HHD encompasses blisters that become erythematous plaques and fissures within flexural areas on a relapsing basis …
Introduction
Benign Familial Pemphigus (Hailey-Hailey Disease [HHD]) is caused by a mutation within ATP2C1, the gene encoding the calcium pump of golgi apparatuses, impacting keratinocytes' ability to adhere to each other, resulting in acantholysis.1 Clinical presentation of HHD encompasses blisters that become erythematous plaques and fissures within flexural areas on a relapsing basis … Continue reading "Management of Hailey-Hailey Disease With Ruxolitinib 1.5% Cream"
At the Skin of Color Update 2024, we had the honor to learn from Dr. Rebecca Vasquez, Associate Professor at UT Southwestern Medical Center, regarding the evolving field of vitiligo management. Vitiligo affects between 0.5% to 2% of the global population, with no racial or gender preference, yet it carries a significant psychological burden for affected individuals.1 Dr. Vasquez emphasized that vi …