Tranexamic Acid Therapeutic Cheat Sheet
Tranexamic acid (TXA) is a synthetic lysine derivative that reversibly blocks the lysine-binding site on plasminogen, preventing conversion to plasmin. While originally developed as an antifibrinolytic agent to reduce bleeding, TXA has several downstream effects that make it useful in dermatology, particularly for pigmentary disorders, with emerging evidence in inflammatory disorders as well. TX …
Tranexamic acid (TXA) is a synthetic lysine derivative that reversibly blocks the lysine-binding site on plasminogen, preventing conversion to plasmin. While originally developed as an antifibrinolytic agent to reduce bleeding, TXA has several downstream effects that make it useful in dermatology, particularly for pigmentary disorders, with emerging evidence in inflammatory disorders as well. TX … 
Leslie Rank, PhD, Global Product Development Lead of Facial Treatment Products, and Rachel Bechtel, Senior Scientist on the Facial Cleansing Product & Process Innovation Team at Kenvue, spoke to dermatology residents at The George Washington University’s first Lab to Label Conference, about the formulation of popular products including dark spot actives, vitamin A derivatives, and cleansers. … 
The many alternatives to hydroquinone make this an exciting time for using cosmeceuticals to treat pigmentary disorders, according to Dr. Heather Woolery-Lloyd, director of the Skin of Color Division at the University of Miami Miller School of Medicine’s Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery. In an interview with Next Steps in Derm, in partnership with Pigmentary Diso … 
Tranexamic acid is one of the latest therapies for treating melasma, and one that’s most commonly prescribed for women. An editorial published in the April issue of the Journal of Drugs in Dermatology encourages dermatology clinicians to also consider the effect melasma has on men and to utilize tranexamic acid as a treatment option.
I interviewed the authors, dermatologist and Mohs surgeon A … 
Introducing the April 2024 Editorial Highlights from the Journal of Drugs in Dermatology! This month's issue is packed with groundbreaking research and insights into dermatologic treatments and practices. From original articles exploring innovative therapies for conditions like photoaging and acne vulgaris to case reports shedding light on rare dermatologic phenomena, this issue offers a comprehen …