Benefits & Pitfalls of Gene Expression Profiling in Treating Cutaneous Malignancies
Next Steps in Derm, in partnership with ODAC Dermatology, Aesthetic and Surgical Conference, interviewed Dr. Vishal A. Patel (fellowship trained Mohs micrographic surgeon who serves as Director of Cutaneous Oncology at the GW Cancer Center and Director of Dermatologic Surgery at the GW Department of Dermatology) about the pros and cons of gene expression profiling. Watch him describe how this tech …
Next Steps in Derm, in partnership with ODAC Dermatology, Aesthetic and Surgical Conference, interviewed Dr. Vishal A. Patel (fellowship trained Mohs micrographic surgeon who serves as Director of Cutaneous Oncology at the GW Cancer Center and Director of Dermatologic Surgery at the GW Department of Dermatology) about the pros and cons of gene expression profiling. Watch him describe how this tech … 
A 65-year-old male patient with a history of chronic sun exposure presents with the lesion pictured that has developed over the past year. The histopathological findings are notable for enlarged keratinocytes infiltrating into the dermis. What type of mutation is most commonly seen in the pathogenesis of this tumor?
A. Transition
B. Transversion
C. Termination
D. Pyrimidine dimer
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This tumor commonly results from mutations in p53. Which of the following is correct?
A. It is the most common type of skin cancer in Caucasians
B. Oral variants most commonly present on the dorsal tongue
C. It is typically less aggressive in patients with CLL
D. plant patients have a 10-fold increased risk of developing this tumor
E. Tumors arising within scars/chronic ulcers h … 
Histologically, this lesion shows plump, polygonal cells arranged in nests and fascicles with granular cytoplasm. Which immunohistochemical stain would be positive?
A. CD31
B. Synaptophysin
C. Factor XIIIa
D. S-100
E. CD34
To find out the correct answer and read the explanation, click here.
Brought to you by our brand partner Derm In-Review. A product of SanovaWorks.
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What would this lesion most likely stain with?
A. S100
B. MART1
C. Giemsa
D. Congo Red
E. Von Kossa
To find out the correct answer and read the explanation, click here.
Brought to you by our brand partner Derm In-Review. A product of SanovaWorks.
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