The correct answer is E. All of the above are features of nevoid BCC syndrome.

The 5 major diagnostic criteria for nevoid BCC syndrome include: 1. Development of >2 BCCs or 1 BCC before the age of 20 2. Odontogenic keratocysts of jaw 3. Palmar or plantar pits (3 or more) 4. Calcification of the falx cerebri 5. 1st degree relative with nevoid BCC syndrome

All the above features are major diagnostic criteria for nevoid BCC syndrome.

References:

Spitz JL. Genodermatoses. Philadelphia: Lipppincott, Williams, and Wilkins, 2005.