A 2-week-old neonate has multiple blisters and erosions on the scalp, trunk, and extremities since birth. New lesions can be induced by mild friction. A biopsy is obtained from an induced blister and demonstrates cleavage at the dermal-epidermal junction and absent type VII collagen on immunofluorescence. What is the most likely genetic mutation and associated condition for this patient?
A. KRT5 or KRT14 (Epidermolysis bullosa simplex)
B. COL7A1 (Dystrophic epidermolysis bullosa)
C. PLEC1 (Junctional epidermolysis bullosa with pyloric atresia)
D. LAMB3 (Junctional epidermolysis bullosa, Herlitz type)
E. DSP (Desmoplakin-related epidermolysis bullosa)
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