The correct answer is A. Alpha agonist which results in contraction of the superior tarsal muscle.

Eyelid ptosis is a known potential complication of glabellar treatment with neurotoxins, likely due to diffusion of medication into the orbit and affecting the levator palpebrae superioris muscle. Apraclonidine is an alpha-agonist which can improve the ptosis by causing contraction of the superior tarsal muscle (occasionally referred to as Müller’s muscle).

The other answer choices do not describe the mechanism of action of apraclonidine.

References: J Neurol Sci. 2017 May 15;376:129-132. Apraclonidine in the treatment of ptosis. Wijemanne S, et al. [https://www.ncbi.nlm.nih.gov/pubmed/28431598]

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