Friday Pop Quiz 4/10/2026
An otherwise healthy 50-year-old male presents with the pictured neoplasm on his trunk. Biopsy reveals melanoma, 2.3mm, ulcerated. Wide local excision and sentinel lymph node biopsy is performed, which is negative. What is the best next step?
A. Observation with skin checks q3 months and symptom-guided imaging
B. Adjuvant pembrolizumab
C. Adjuvant dabrafenib + trametinib
D. Adjuv …
An otherwise healthy 50-year-old male presents with the pictured neoplasm on his trunk. Biopsy reveals melanoma, 2.3mm, ulcerated. Wide local excision and sentinel lymph node biopsy is performed, which is negative. What is the best next step?
A. Observation with skin checks q3 months and symptom-guided imaging
B. Adjuvant pembrolizumab
C. Adjuvant dabrafenib + trametinib
D. Adjuv … 
What trichoscopic finding in the pictured condition is associated with the most favorable prognosis?
A. Yellow dots
B. White dots
C. Loss of follicular ostia
D. Perifollicular erythema
E. Peripilar casts
To find out the correct answer and read the explanation, click here.
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A 50-year-old-male presents to clinic with a pruritic, linear distributed rash that has been present for two weeks without any other involvement (such as scalp or nails). On examination, there is a linearly arranged eczematous papular eruption on the right flank. What is the best diagnosis?
A. Blaschkitis
B. Psoriasis (linear)
C. Herpes simplex
D. Factitial condition
E. Linear l … 
What histologic features are typically seen on a skin biopsy of this lesion?
A. Necrobiotic degeneration of dermal collagen surrounded by an inflammatory reaction
B. Layers with open-ended necrobiotic foci; lack of mucin; increased numbers of plasma cells (necrobiosis lipoidica)
C. Larger areas of eosinophilic necrobiosis and a lack of mucin deposition (rheumatoid nodule)
D. Immuno … 
A 75-year-old man presents with tense bullae as pictured. DIF reveals linear IgG and C3 at the dermal-epidermal junction. On salt-split skin, immunoreactants are localized to the roof of the specimen. What is the target antigen?
A. Type VII Collagen
B. Type XVII collagen (BP180)
C. Laminin 332
D. Desmoglein 1
E. Integrin α6β4
To find out the correct answer and read the expl …