Colchicine Therapeutic Cheat Sheet
Colchicine, a microtubule polymerization inhibitor, was first described for use in treating joint pain and swelling in ancient Egypt and has since become a mainstay in the medical management of gout. Beyond its indicated uses, it has numerous off-label dermatologic applications, particularly for neutrophilic and autoimmune conditions. As a potent anti-inflammatory, colchicine requires careful lab …
Colchicine, a microtubule polymerization inhibitor, was first described for use in treating joint pain and swelling in ancient Egypt and has since become a mainstay in the medical management of gout. Beyond its indicated uses, it has numerous off-label dermatologic applications, particularly for neutrophilic and autoimmune conditions. As a potent anti-inflammatory, colchicine requires careful lab … 
Ivermectin is a semi-synthetic derivative of avermectins, a class of macrocyclic lactones with broad-spectrum anti-parasitic effects. Its unique mechanism of action, favorable safety profile, and anti-inflammatory properties make ivermectin invaluable in the treatment of a wide range of cutaneous parasitic infestations, including scabies. We continue our series, Therapeutic Cheat Sheet, with a cl … 
Atopic dermatitis and prurigo nodularis are chronic, life-altering diseases with a common feature of debilitating pruritus that significantly impacts our patients’ qualities of life. For those with resistant and extensive disease, dermatologists now have nemolizumab in our armamentarium, the first FDA approved IL-31 inhibitor. We continue our series, Therapeutic Cheat Sheet, with a closer look a … 
Permethrin is a synthetic neurotoxic pyrethroid derived from chrysanthemums with significant dermatologic value for its powerful insecticide properties when used topically. We continue our series, Therapeutic Cheat Sheet, with a closer look at permethrin, which is FDA-approved for the treatment of scabies and pediculosis capitis infestations.
Permethrin Therapeutic Cheat Sheet
Compiled by: Dillo … 
Ketoconazole is an imidazole antifungal that was initially FDA-approved in an oral formulation for the treatment of systemic fungal infections. While oral ketoconazole has largely fallen out of use due to safety concerns, including hepatotoxicity, endocrine dysregulation, and drug interactions, topical ketoconazole has proven to be a safe and effective treatment for superficial fungal infections. … 