Urticaria Pigmentosa Without Pruritus | Case Report
urticaria pigmentosa Mastocytosis is a group of disorders characterized by the pathologic accumulation of mast cells in various tissues. One example of mastocytosis is urticaria pigmentosa, which presents with mastocytomas that can cause hives and, when irritated, pruritus. To the authors' knowledge, they are describing the first case of urticaria pigmentosa without pruritus. The patient had a positive Darier' …
urticaria pigmentosa
Ruxolitinib 1.5% Topical Cream for the Treatment of Pediatric Alopecia Areata | Case Report
pediatric alopeciaAlopecia areata (AA) is a common autoimmune disorder. Although its pathogenesis is not fully understood, AA involves CD8 T cell-mediated destruction of the hair follicle. Several treatment options exist; however, there is minimal evidence in the pediatric population. Currently, there are no curative treatments for AA. The literature suggests that Janus kinase (JAK) inhibitors may be an effective t …
pediatric alopecia
A Massive Case of Cutaneous Diffuse Large B-Cell Lymphoma
B-Cell LymphomaABSTRACT Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma, and extranodal involvement is seen in approximately 40% of cases. However, cases involving the skin and muscle are rare, and skin manifestations most commonly present as plaques, papules, small nodules, or ulcers. In this report, JDD authors Lauren E. Merz MD MSc, Christopher B. Hergott MD PhD, and Reb …
B-Cell Lymphoma
Post-Hyaluronic Acid Filler Reaction Treated With Abrocitinib: A Case Report
hyaluronic acidABSTRACT Post-hyaluronic acid filler nodules are uncommon, unpredictable complications that present a challenge to clinical therapy. JDD authors Miyahra Haniko P. Lopez MD MBA, Sophie H. Guenin MSc, Jennifer Laborada BS, and Mark G. Lebwohl MD report a case of a female in her fifties who developed edema and nodules 6 weeks after hyaluronic acid (HA) filler injection. After minimal improvement wit …
hyaluronic acid
Atypical Dyschromia in Skin of Color
DyschromiaABSTRACT Dyschromia is a concern for many patients, especially persons of color. Postinflammatory hypopigmentation and depigmentation can affect all skin types; however, it is more apparent in those with darker skin. Some members of the dermatology community may not comprehensively understand the mechanisms of these reactions and the extent of the psychosocial effect they have on persons of color …
Dyschromia