Alopecia Universalis: Never Give Up?
alopecia universalisINTRODUCTION Alopecia universalis is a type of alopecia areata (AA) characterized by total body hair loss. The mechanism of this loss is primarily due to autoimmune disruption of the hair follicle. AA has historically been treated with corticosteroids, minoxidil, and other immune therapies that possess limited efficacy with high recurrence rates and adverse effects.1 However, in recent years the …
alopecia universalis
Co-occurring Melanoma in an Active Area of Vitiligo in Skin of Color
vitiligo The association between vitiligo and melanoma is complex. While the incidence of vitiligo in patients with melanoma is higher, the risk for the reverse, ie, the development of melanoma in a patient with vitiligo, is thought to be decreased. This report presents a case of melanoma developing on a non-sun-exposed site in a patient with skin of color and untreated vitiligo. It emphasizes the need …
vitiligo
Hyperpigmented Macules and Patches on the Face: Exogenous Ochronosis or Lichen Planus Pigmentosus?
Exogenous Ochronosis (EO)JDD authors Deepika Narayanan, MD and Stephen K. Tyring, MD, PhD, MBA present a case of a patient with a 10-year history of blue-black macules and patches on the face and an associated history of skin- lightening cream usage. The skin lightening cream contained hydroquinone, which is often associated with exogenous ochronosis (EO). Interestingly, the biopsy did not show characteristic findings of …
Exogenous Ochronosis (EO)
Case Series of Acral and Mucosal Melanoma in a Diverse Patient Population
acral melanomaINTRODUCTION Melanoma accounts for only 1% of all skin cancers but is responsible for most skin cancer-related deaths.1 Acral and mucosal melanoma (AMM) accounts for only 4% of all new melanomas but is associated with poorer prognosis.2 Patients of color are disproportionately affected by AMM. Elucidating the clinical, genetic, and environmental features of AMM can guide advancements in the …
acral melanoma
Inverse Eruptive Syringoma in a Skin of Color Patient
SyringomaSyringomas are benign neoplasms derived from eccrine sweat glands. Eruptive syringomas are a subtype of syringomas and are typically located on the chest, neck, and abdomen during puberty or childhood. Herein, JDD authors Jennifer Wang BA, Nyousha Yousefi MD, Edward Heilman MD FAAD FCAP, and Jared Jagdeo MD MS present a 20-year-old African American female with an atypical case of eruptive syringom …
Syringoma