Gut-Immune-Skin Axis: What Happens in the Gut Matters to the Skin
Gut-Immune-Skin AXISThe gut-immune-skin axis describes how the gut microbiome communicates with the skin via complex interactions with the immune system to regulate local and systemic inflammation. Before attempting to delineate that relationship, we must first grasp a firm understanding of the gut ecosystem. The gut ecosystem is made up of the epithelial interface, which is characterized by the epithelial …
Gut-Immune-Skin AXIS
Pop Quiz #127
The correct answer is D. Dermatomyositis.  Manifestations of dermatomyositis range from poikiloderma of the scalp to centripetal flagellate erythema to erosions and ulcerations. It is also important to look for dermatologic signs of other connective tissue diseases in patients with dermatomyositis, because of the frequency of overlap syndromes. The most common cutaneous findings would be s …
Pregabalin for Chronic Pruritus | Therapeutic Cheat Sheet
Chronic pruritus affects 8-16% of the general population and has a profound impact on patient quality of life.1-3Although the symptom of pruritus may originate from a number of underlying etiologies, including metabolic derangements and infectious causes, along with neoplastic, inflammatory, or psychiatric conditions, other cases may be idiopathic in nature.4 Given the diversity of underlying cont …
Naltrexone for Pruritus – Therapeutic Cheat Sheet
Naltrexone for pruritusPruritus, whether related to inflammatory skin conditions or systemic disease, can be debilitating for patients. In order to improve quality of life for patients suffering from severe pruritus, dermatologists often resort to off-label use of systemic medications. In this month’s installment of our Therapeutic Cheat Sheet Series, we will discuss use of naltrexone for treatment of pruritus. Naltr …
Naltrexone for pruritus
Treatment of Atopic Dermatitis with Chinese Herbal Medicine
Chinese Herbal Medicine Approach to Atopic DermatitisWe are constantly learning in dermatology.  With advents of new techniques, sometimes traditional methods can be forgotten or lost.  Chinese Herbal Medicine dates back thousands of years.  Just as we shouldn’t retire chemical peels in favor of a “laser-only” approach, maybe we shouldn’t give up on other traditional methods. During the 2020 Integrative Dermatology Symposium, Dr. Trevo …
Chinese Herbal Medicine Approach to Atopic Dermatitis
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