Utility of Pulsed-Dye Laser in the Treatment of Recalcitrant Hailey-Hailey Disease
INTRODUCTION
Benign Familial Pemphigus, or Hailey-Hailey Disease (HHD), affects intertriginous areas of the skin causing epidermal blistering and vesicles that coalesce into weeping and crusting plaques.¹
The loss-of-function mutation of the ATP2C1 gene causes a disruption in calcium homeostasis of keratinocytes. The resulting dysfunction in desmosomes and cell-cell adhesion causes acanthol …
INTRODUCTION
Benign Familial Pemphigus, or Hailey-Hailey Disease (HHD), affects intertriginous areas of the skin causing epidermal blistering and vesicles that coalesce into weeping and crusting plaques.¹
The loss-of-function mutation of the ATP2C1 gene causes a disruption in calcium homeostasis of keratinocytes. The resulting dysfunction in desmosomes and cell-cell adhesion causes acanthol … 
Current field-directed treatments of actinic keratosis (AK), a pre-malignant condition, are often limited by severe local reactions and/or complex treatment. Tirbanibulin, a novel potent anti-proliferative synthetic agent that inhibits tubulin polymerization and Src kinase signalling, offers a convenient, safe, and effective field treatment of actinic keratosis. We continue our surgical Therapeut … 
Which of the following conditions is most associated with the findings in this 9-year-old boy?
A. Alopecia areata
B. Atopic dermatitis
C. Neurofibromatosis I
D. Parkinson disease
E. Tuberous sclerosis
To find out the correct answer and read the explanation, click here.
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Next Steps in Derm, in partnership with Pigmentary Disorders Exchange Symposium, interviewed Dr. Heather Woolery-Lloyd, director of the Skin of Color Division for the University of Miami Department of Dermatology. Watch as Dr. Woolery-Lloyd outlines the role of superficial chemical peels in treating pigmentary disorders. Learn how chemical peels impact other treatments. Find out her chemical peel … 
Fluconazole is a synthetic triazole with a broader antifungal spectrum than the imidazole class. Resistance to first-pass metabolism and consistent oral absorption are advantages over agents like ketoconazole in the antifungal armamentarium, particularly in the context of the United States Food and Drug Administration’s reinforced warning against oral ketoconazole for skin and nail infections, d …