Alitretinoin Therapeutic Cheat Sheet
alitretinoinAlitretinoin (9-cis-retinoic acid) is a naturally occurring endogenous retinoid that in gel form is FDA approved for AIDs-related localized cutaneous Kaposi’s sarcoma (KS)1. As compared to other topical retinoids, alitretinoin is unique in that it binds to all known intracellular retinoid receptors (RARs and RXRs), allowing it to exert anti-proliferative and apoptotic effects, particularly usefu …
Skincare Mondays | Regrounding on Retinoids
retinoidsRetinoids Retinoids are a class of molecules derived from vitamin A or having structural and/or functional similarities to vitamin A.1 The first medicinal use of vitamin A dates back to ancient Egypt where liver juices were used to treat endemic night blindness.2 Prescribed topical retinoids are divided into 6 classes: Tretinoin (all-trans retinoic acid), adapalene, tazarotene, trifarotene, al …