Darier's sign

Urticaria Pigmentosa Without Pruritus | Case Report
urticaria pigmentosa Mastocytosis is a group of disorders characterized by the pathologic accumulation of mast cells in various tissues. One example of mastocytosis is urticaria pigmentosa, which presents with mastocytomas that can cause hives and, when irritated, pruritus. To the authors' knowledge, they are describing the first case of urticaria pigmentosa without pruritus. The patient had a positive Darier' …
urticaria pigmentosa
It’s Mnemonic Monday! Stains for Mast Cells
stains for mast cellsOn this Mnemonic Monday, we challenge you to remember stains for Mast cells. "GIMME TO YOUR LEDER" Giemsa Toluidine blue Leder Remember  "rub me and take me to your Leder" as a mnemonic to remember that Leder stain still works after Darier's sign is induced (after de-granulation of mast cells). Side note: Not all stains are included here. Ex: tryptase and c-kit would also stain mast …
stains for mast cells