Alopecia Universalis: Never Give Up?
INTRODUCTION
Alopecia universalis is a type of alopecia areata (AA) characterized by total body hair loss. The mechanism of this loss is primarily due to autoimmune disruption of the hair follicle. AA has historically been treated with corticosteroids, minoxidil, and other immune therapies that possess limited efficacy with high recurrence rates and adverse effects.1 However, in recent years the …
INTRODUCTION
Alopecia universalis is a type of alopecia areata (AA) characterized by total body hair loss. The mechanism of this loss is primarily due to autoimmune disruption of the hair follicle. AA has historically been treated with corticosteroids, minoxidil, and other immune therapies that possess limited efficacy with high recurrence rates and adverse effects.1 However, in recent years the … 
JDD authors Deepika Narayanan, MD and Stephen K. Tyring, MD, PhD, MBA present a case of a patient with a 10-year history of blue-black macules and patches on the face and an associated history of skin- lightening cream usage. The skin lightening cream contained hydroquinone, which is often associated with exogenous ochronosis (EO). Interestingly, the biopsy did not show characteristic findings of … 
JDD authors Mihir Shah MD, Jenna Wald MD, and C. William Hanke MD MPH present a case of a patient with eruptive squamous cell carcinomas following treatment with Fludarabine to highlight not only the risk of cSCC in CLL patients and the increased risk for atypical cutaneous malignancies after treatment with systemic therapies such as fludarabine, but also to discuss treatment options for this … 
Rosacea is a chronic inflammatory skin condition characterized by facial flushing, erythema, telangiectasias, and papulopustular lesions. Treatment for rosacea includes limiting inciting factors and reducing inflammation with topical and oral therapies. Traditional therapies primarily focus on the papulopustular or background erythematotelangiectatic component of rosacea, leaving symptoms of flush … 
Perniosis (also known as pernio or chilblains), is a condition characterized by the development of pruritic, painful erythrocyanotic skin lesions induced by exposure to cold temperatures.² When perniosis occurs in conjunction with clinical or laboratory features of systemic lupus erythematosus, the condition is further classified as chilblain lupus erythematosus (CHLE). CHLE is a rare condition w … 