dermatology case report

Severe Ulcerative Perniosis Treated With Botulinum Toxin
Botulinum Toxin
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Perniosis (also known as pernio or chilblains), is a condition characterized by the development of pruritic, painful erythrocyanotic skin lesions induced by exposure to cold temperatures.² When perniosis occurs in conjunction with clinical or laboratory features of systemic lupus erythematosus, the condition is further classified as chilblain lupus erythematosus (CHLE). CHLE is a rare condition w …

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Successful Use of Tildrakizumab for Treatment of Palmoplantar Pustulosis
Palmoplantar Pustulosis
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Palmoplantar pustulosis (PPP) is a rare, recurrent skin disorder that presents a major challenge to clinical therapy. JDD author Danilo C. Del Campo, MD, FAAD reports a case of a 69-year-old woman with a 20-year history of psoriasis with skin manifestations and clinical and pathologic features consistent with PPP. After intolerance to apremilast and unsuccessful use of topical corticosteroids and …

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Topical Cannabinoids for the Management of Psoriasis Vulgaris
Cannabinoids for Psoriasis
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Authors Adam J. Friedman MD, Kimia Momeni BS, and Mikhail Kogan MD present a case of a young man with psoriasis managed with topical cannabinoids. Introduction The interest in use of medical cannabis for chronic dermatologic conditions such as psoriasis, eczema, and acne has been growing mostly owing to rapidly emerging decriminalization across the country and impressive commercially driven popu …

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Hand Foot Skin Reaction Associated With Palbociclib
Palbociclib
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INTRODUCTION Palbociclib is one of three new small-molecule inhibitors of cyclin-dependent kinase 4 and 6 (CDK4/6) approved for use in the treatment of hormone receptor positive (HR+) and human epidermal growth factor receptor 2 negative (Her2-) advanced or metastatic breast cancer. CDK4/6 inhibitors have a good overall safety profile but reported side effects include cytopenias, diarrhea, QTc pr …

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Recurrent Squamous Cell Carcinoma Arising Within a Linear Porokeratosis
SCC
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JDD authors Amelia M. Abbott-Frey BA, Alexandra J. Coromilas MD, George W. Niedt MD, and Jesse M. Lewin MD report a case of linear porokeratosis with recurrent malignant degeneration to squamous cell carcinoma (SCC) recurring six years after excision of initial SCC. Case Report A 79-year-old woman with a history of hypertension and hypothyroidism presented with a friable tumor within a lesion o …

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