Friday Pop Quiz 11/12/2025
A 40-year-old female presents for a scalp biopsy. On histology, you note premature desquamation of the inner root sheath, eccentric epithelial atrophy with hair shafts in close proximity to the dermis, and concentric lamellar fibroplasia of some follicles. There is variably dense lymphocytic perifollicular inflammation, primarily at the level of the upper isthmus and lower infundibulum. There …
A 40-year-old female presents for a scalp biopsy. On histology, you note premature desquamation of the inner root sheath, eccentric epithelial atrophy with hair shafts in close proximity to the dermis, and concentric lamellar fibroplasia of some follicles. There is variably dense lymphocytic perifollicular inflammation, primarily at the level of the upper isthmus and lower infundibulum. There … 
A 2-year-old male with recurrent flares of the pictured findings developed non-tender nodules on his bilateral thighs. What would likely establish the diagnosis?
A. Genetic testing for STAT3 and DOCK8 mutations
B. Genetic testing for SPINK5 mutations
C. Obtaining immunoglobulin E levels
D. Obtaining serum zinc levels
E. Flow cytometry to evaluate CD18 expression
To find out the … 
What is the minimum amount of time that you would advise this woman to avoid pregnancy after completing a course of isotretinoin?
A. 1 week
B. 1 month
C. 6 months
D. 1 year
E. 3 years
To find out the correct answer and read the explanation, click here.
The image is from The Full Spectrum of Dermatology: A Diverse and Inclusive Atlas.
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There are four types of Kaposi Sarcoma. The viral strain associated with classic AIDS-associated Kaposi Sarcoma is:
A. HHV-8
B. HHV-6
C. HHV-5
D. HHV-4
E. HHV-3
To find out the correct answer and read the explanation, click here.
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What is the most common associated mutation with the condition shown here?
A. HGD
B. HFE
C. COL1A1
D. GNAQ
E. POMC
To find out the correct answer and read the explanation, click here.
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