My Approach to Diagnosing Systemic Disease
Diagnosing systemic disease requires connecting the dots from the microscope to the bedside, according to Mayo Clinic dermatologist and dermatopathologist Olayemi Sokumbi, MD, FAAD.
In this Next Steps in Derm interview, in partnership with the ODAC Dermatology Conference, Dr. Sokumbi outlines how she makes diagnostic decisions, including thinking beyond the skin. As a dermatologic detective of …
Diagnosing systemic disease requires connecting the dots from the microscope to the bedside, according to Mayo Clinic dermatologist and dermatopathologist Olayemi Sokumbi, MD, FAAD.
In this Next Steps in Derm interview, in partnership with the ODAC Dermatology Conference, Dr. Sokumbi outlines how she makes diagnostic decisions, including thinking beyond the skin. As a dermatologic detective of … Continue reading "My Approach to Diagnosing Systemic Disease"
What histologic features are typically seen on a skin biopsy of this lesion?
A. Necrobiotic degeneration of dermal collagen surrounded by an inflammatory reaction
B. Layers with open-ended necrobiotic foci; lack of mucin; increased numbers of plasma cells (necrobiosis lipoidica)
C. Larger areas of eosinophilic necrobiosis and a lack of mucin deposition (rheumatoid nodule)
D. Immuno … 
Which of the following is true regarding this entity?
A. The subcutaneous variant is most common in children
B. 75% of localized lesions are still present 2 years after diagnosis
C. Localized lesions often ulcerate and heal with scarring
D. The perforating variant classically involves the lower extremities
E. Diabetes is present in the majority of patients with the generalized v … 
Pentoxifylline is a methyl-xanthine derivative traditionally used to treat symptoms of peripheral vascular disease and has emerged as a valuable therapeutic agent in dermatology for its anti-inflammatory and immunomodulatory properties. We continue our series, Therapeutic Cheat Sheet, with a closer look at pentoxifylline, which is FDA-approved for the treatment of intermittent claudication and is … 
Next Steps in Derm and the Journal of Drugs in Dermatology, in partnership with the Dermatology Education Foundation (DEF) and Physicians Resources, interviewed Dr. Ted Rosen (Professor, Vice-Chair of Dermatology, and Chief of Dermatology at the Houston Veterans Affairs Medical Center) on his favorite off-label treatment pearls. Watch as he shares how to use indomethacin for the angry red scrot …