Tranexamic Acid Therapeutic Cheat Sheet
Tranexamic acid (TXA) is a synthetic lysine derivative that reversibly blocks the lysine-binding site on plasminogen, preventing conversion to plasmin. While originally developed as an antifibrinolytic agent to reduce bleeding, TXA has several downstream effects that make it useful in dermatology, particularly for pigmentary disorders, with emerging evidence in inflammatory disorders as well. TX …
Tranexamic acid (TXA) is a synthetic lysine derivative that reversibly blocks the lysine-binding site on plasminogen, preventing conversion to plasmin. While originally developed as an antifibrinolytic agent to reduce bleeding, TXA has several downstream effects that make it useful in dermatology, particularly for pigmentary disorders, with emerging evidence in inflammatory disorders as well. TX … 
Hyperpigmentation often drives dermatology visits for patients with skin of color as an uneven skin tone can be distressing for patients. In fact, in cases where hyperpigmentation is a sequelae of an inflammatory skin condition, the hyperpigmentation can be more concerning for patients than the skin condition that caused it. Globally and in the U.S., this distress can lead patients to self-treat w … 
Post-acne scars can be disfiguring and require a creative treatment approach in patients with skin of color, according to Dr. Michelle Henry, clinical instructor of dermatology at Weill Cornell Medical College. Next Steps in Derm, in partnership with Skin of Color Update, interviewed Dr. Henry, who shared what energy-based devices she uses in her practice and how she chooses a device based on a p … 
Recent advances in photodermatology have expanded our understanding of how multiple wavelengths across the electromagnetic spectrum contribute to skin damage, aging, pigmentary disorders, and skin cancer risk. While ultraviolet (UV) radiation has traditionally been the primary focus of sun protection, visible light (VL), high-energy visible (HEV) light, infrared (IR) radiation, and even heat have … 
There is more than meets the eye when it comes to diagnosing dermatologic disease. At the most recent Skin of Color Update conference in New York City, co-chair Dr. Andrew Alexis gave a case-based presentation on dermatologic clues to systemic disease in patients with skin of color. The cases highlighted how subtle pigmentary and textural changes in the skin can be the first presenting sign of …