JDD case report

Successful Use of Tildrakizumab for Treatment of Palmoplantar Pustulosis
Palmoplantar Pustulosis
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Palmoplantar pustulosis (PPP) is a rare, recurrent skin disorder that presents a major challenge to clinical therapy. JDD author Danilo C. Del Campo, MD, FAAD reports a case of a 69-year-old woman with a 20-year history of psoriasis with skin manifestations and clinical and pathologic features consistent with PPP. After intolerance to apremilast and unsuccessful use of topical corticosteroids and …
Topical Cannabinoids for the Management of Psoriasis Vulgaris
Cannabinoids for Psoriasis
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Authors Adam J. Friedman MD, Kimia Momeni BS, and Mikhail Kogan MD present a case of a young man with psoriasis managed with topical cannabinoids. Introduction The interest in use of medical cannabis for chronic dermatologic conditions such as psoriasis, eczema, and acne has been growing mostly owing to rapidly emerging decriminalization across the country and impressive commercially driven popu …
Temporal Suspension Flap for Malar Defects
malar defects
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BACKGROUND The upper lateral cheek bears unique and distinct local characteristics that are key features in facial aesthetics and functionality. Its main landmarks are the lower eyelid, the lateral canthus, and the temporal hairline. When contemplating treatment options for defects in this area, the surgeon should take into consideration the possible effects of the reconstructive method on the pr …
Hand Foot Skin Reaction Associated With Palbociclib
Palbociclib
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INTRODUCTION Palbociclib is one of three new small-molecule inhibitors of cyclin-dependent kinase 4 and 6 (CDK4/6) approved for use in the treatment of hormone receptor positive (HR+) and human epidermal growth factor receptor 2 negative (Her2-) advanced or metastatic breast cancer. CDK4/6 inhibitors have a good overall safety profile but reported side effects include cytopenias, diarrhea, QTc pr …
Treatment of Periorificial Dermatitis With Novel Narrow Spectrum Sarecycline
Periorificial Dermatitis
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Broad spectrum tetracyclines are a well-known, widely used, and often successful treatment for use in inflammatory skin pathologies such as acne and rosacea. However, the steady rise of antibiotic resistance and gut dysbiosis associated with broad spectrum tetracyclines emphasizes the importance and responsibility of antibiotic stewardship. Narrow spectrum antibiotics have become increasingly impo …