Alopecia Universalis: Never Give Up?
INTRODUCTION
Alopecia universalis is a type of alopecia areata (AA) characterized by total body hair loss. The mechanism of this loss is primarily due to autoimmune disruption of the hair follicle. AA has historically been treated with corticosteroids, minoxidil, and other immune therapies that possess limited efficacy with high recurrence rates and adverse effects.1 However, in recent years the …
INTRODUCTION
Alopecia universalis is a type of alopecia areata (AA) characterized by total body hair loss. The mechanism of this loss is primarily due to autoimmune disruption of the hair follicle. AA has historically been treated with corticosteroids, minoxidil, and other immune therapies that possess limited efficacy with high recurrence rates and adverse effects.1 However, in recent years the …
JDD authors present the case of a 38-year-old male who reported to their practice with multiple newly developed halos around 26 existing nevi on his trunk. The halo nevi developed after the patient, who lived in the northeast, spent 2 months on a lake in Alabama, with intense heat and sun exposure. This case is remarkable in that it points to ultraviolet exposure as one instigating factor in the …
JDD authors Mihir Shah MD, Jenna Wald MD, and C. William Hanke MD MPH present a case of a patient with eruptive squamous cell carcinomas following treatment with Fludarabine to highlight not only the risk of cSCC in CLL patients and the increased risk for atypical cutaneous malignancies after treatment with systemic therapies such as fludarabine, but also to discuss treatment options for this …
In this brief communication, JDD authors T. Roxana Ghadimi BS, Michael J. Martinez BS, and Evan A. Rieder MD present self-reported long-term, remote side effects to isotretinoin that dermatologists must be aware of.
INTRODUCTION
Isotretinoin is considered the gold standard treatment for severe nodulocystic acne, though it has been the subject of controversy in the media for concerns relate …
INTRODUCTION
Linear lichen planus pigmentosus (LPP) of the face is a rare acquired variant of lichen planus, with only a few cases published in the literature.1 It is an inflammatory condition with unknown etiology, characterized by blue-gray hyperpigmented macules, and tends to affect sun-exposed areas of the head and neck.1-4 The pathophysiology of linear LPP is poorly understood, though …