Urticaria Pigmentosa Without Pruritus | Case Report
Mastocytosis is a group of disorders characterized by the pathologic accumulation of mast cells in various tissues. One example of mastocytosis is urticaria pigmentosa, which presents with mastocytomas that can cause hives and, when irritated, pruritus. To the authors' knowledge, they are describing the first case of urticaria pigmentosa without pruritus. The patient had a positive Darier' …
Mastocytosis is a group of disorders characterized by the pathologic accumulation of mast cells in various tissues. One example of mastocytosis is urticaria pigmentosa, which presents with mastocytomas that can cause hives and, when irritated, pruritus. To the authors' knowledge, they are describing the first case of urticaria pigmentosa without pruritus. The patient had a positive Darier' … Continue reading "Urticaria Pigmentosa Without Pruritus | Case Report"
The neoplasm shown is made of cells that are most likely to contain which of the following substances?
A. Histamine
B. Antibodies
C. Major basic protein
D. Melanin
E. Myeloperoxidases
To find out the correct answer and read the explanation, click here.
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Which organ system is least likely to be involved in the condition shown in the attached image?
A. Liver
B. Spleen
C. Genitourinary
D. Gastrointestinal tract
E. Bone marrow
To find out the correct answer and read the explanation, click here.
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On this Mnemonic Monday, we challenge you to remember stains for Mast cells.
"GIMME TO YOUR LEDER"
Giemsa
Toluidine blue
Leder
Remember "rub me and take me to your Leder" as a mnemonic to remember that Leder stain still works after Darier's sign is induced (after de-granulation of mast cells). Side note: Not all stains are included here. Ex: tryptase and c-kit would also stain mast … 