Friday Pop Quiz 11/7/2025
A 2-year-old male with recurrent flares of the pictured findings developed non-tender nodules on his bilateral thighs. What would likely establish the diagnosis?
A. Genetic testing for STAT3 and DOCK8 mutations
B. Genetic testing for SPINK5 mutations
C. Obtaining immunoglobulin E levels
D. Obtaining serum zinc levels
E. Flow cytometry to evaluate CD18 expression
To find out the …
A 2-year-old male with recurrent flares of the pictured findings developed non-tender nodules on his bilateral thighs. What would likely establish the diagnosis?
A. Genetic testing for STAT3 and DOCK8 mutations
B. Genetic testing for SPINK5 mutations
C. Obtaining immunoglobulin E levels
D. Obtaining serum zinc levels
E. Flow cytometry to evaluate CD18 expression
To find out the … 
ABSTRACT
Post-hyaluronic acid filler nodules are uncommon, unpredictable complications that present a challenge to clinical therapy. JDD authors Miyahra Haniko P. Lopez MD MBA, Sophie H. Guenin MSc, Jennifer Laborada BS, and Mark G. Lebwohl MD report a case of a female in her fifties who developed edema and nodules 6 weeks after hyaluronic acid (HA) filler injection. After minimal improvement wit … 
A pool worker develops these painful erythematous nodules with ulceration on his fingers and then his arms. Which of the following is the most appropriate treatment?
A. Penicillin
B. Ceftriaxone
C. Minocycline
D. Trimethoprim-sulfamethoxasole
E. Cephalexin
To find out the correct answer and read the explanation, click here.
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