Roflumilast Therapeutic Cheat Sheet
Roflumilast is a non-steroidal topical cream that was FDA approved for the treatment of plaque psoriasis in 2022.1 Roflumilast selectively inhibits phosphodiesterase-4 (PDE-4), which is an enzyme that mediates inflammatory responses and has been shown to play a role in several dermatologic diseases.2 Prior to topical roflumilast, oral PDE-4 inhibitors have been investigated across a wide variety o …
Roflumilast is a non-steroidal topical cream that was FDA approved for the treatment of plaque psoriasis in 2022.1 Roflumilast selectively inhibits phosphodiesterase-4 (PDE-4), which is an enzyme that mediates inflammatory responses and has been shown to play a role in several dermatologic diseases.2 Prior to topical roflumilast, oral PDE-4 inhibitors have been investigated across a wide variety o … 
As part of the recent 2020 Integrative Dermatology Symposium, Dr. Jason Hawkes, Associate Clinical Professor of Dermatology at UC Davis, provided a fantastically comprehensive primer on the management of psoriasis in the COVID-19 era. Read on for important treatment recommendations and insights to improve your clinical practice!
As an introduction, Dr. Hawkes emphasized that psoriasis remains a … 