rash

Friday Pop Quiz 11/1/2024
An 8-month-old boy is brought in by his mother for concerns of a rash that comes and goes for the last few months, primarily on his face and belly. His older brother suffers from asthma and often has a similar rash on the inside of his elbow and behind his knees. Lead-in Question: The gene most commonly mutated in the photograph is also mutated in which of the following? A. Palmoplantar ker …
Friday Pop Quiz 10/4/2024
A 23-year-old female presents with itchy and irritated rash in the image. The rash began in her late teens. She has a family history of similar rash in her mother. Which histocompatibility antigen is most likely in this patient? A. HLA-Cw2 B. HLA-Cw6 C. HLA-B51 D. HLA-B27 E. HLA-Bw35 To find out the correct answer and read the explanation, click here. Brought to you by our bra …
Calling All Derms! Chronic Spontaneous Urticaria Is For You!
chronic spontaneous urticariaAt the 2024 ODAC Dermatology, Aesthetic & Surgical Conference, we were lucky to learn about the management of chronic spontaneous urticaria (CSU) from the renowned researcher and clinician, Dr. Adam J. Friedman, Professor and Chair of Dermatology at The George Washington University School of Medicine and Health Sciences. CSU can be a frustrating, exhausting condition for patients to endure, wi …
chronic spontaneous urticaria
Utility of Pulsed-Dye Laser in the Treatment of Recalcitrant Hailey-Hailey Disease
Hailey-Hailey Disease INTRODUCTION Benign Familial Pemphigus, or Hailey-Hailey Disease (HHD), affects intertriginous areas of the skin causing epidermal blistering and vesicles that coalesce into weeping and crusting plaques.¹ The loss-of-function mutation of the ATP2C1 gene causes a disruption in calcium homeostasis of keratinocytes. The resulting dysfunction in desmosomes and cell-cell adhesion causes acanthol …
Hailey-Hailey Disease
Skin Pustules – Friday Pop Quiz 1/20/2023
A patient comes in with the rash pictured below consisting of pustules in an annular or polycyclic configuration. What type of paraproteinemia can this disorder be associated with and thus a workup should be initiated for? A. IgG kappa B. IgG lambda C. IgA D. IgM E. IgD To find out the correct answer and read the explanation, click here.    Brought to you by our brand …