Friday Pop Quiz 3/21/2025
A 15-year-old girl who recently moved from India to the United States presents to dermatology clinic with chief concern of the pictured rash. She has previously undergone treatment with 4 weeks of daily terbinafine, as well as 6 weeks of fluconazole, without resolution. KOH reveals numerous branching hyphae.
Which of the following is the most appropriate next step?
A. Initiate topica …
A 15-year-old girl who recently moved from India to the United States presents to dermatology clinic with chief concern of the pictured rash. She has previously undergone treatment with 4 weeks of daily terbinafine, as well as 6 weeks of fluconazole, without resolution. KOH reveals numerous branching hyphae.
Which of the following is the most appropriate next step?
A. Initiate topica … 
An 8-month-old boy is brought in by his mother for concerns of a rash that comes and goes for the last few months, primarily on his face and belly. His older brother suffers from asthma and often has a similar rash on the inside of his elbow and behind his knees. Lead-in Question: The gene most commonly mutated in the photograph is also mutated in which of the following?
A. Palmoplantar ker … 
A 23-year-old female presents with itchy and irritated rash in the image. The rash began in her late teens. She has a family history of similar rash in her mother. Which histocompatibility antigen is most likely in this patient?
A. HLA-Cw2
B. HLA-Cw6
C. HLA-B51
D. HLA-B27
E. HLA-Bw35
To find out the correct answer and read the explanation, click here.
Brought to you by our bra … 
At the 2024 ODAC Dermatology, Aesthetic & Surgical Conference, we were lucky to learn about the management of chronic spontaneous urticaria (CSU) from the renowned researcher and clinician, Dr. Adam J. Friedman, Professor and Chair of Dermatology at The George Washington University School of Medicine and Health Sciences. CSU can be a frustrating, exhausting condition for patients to endure, wi … 
INTRODUCTION
Benign Familial Pemphigus, or Hailey-Hailey Disease (HHD), affects intertriginous areas of the skin causing epidermal blistering and vesicles that coalesce into weeping and crusting plaques.¹
The loss-of-function mutation of the ATP2C1 gene causes a disruption in calcium homeostasis of keratinocytes. The resulting dysfunction in desmosomes and cell-cell adhesion causes acanthol … 