JDD Buzz Series | Minoxidil for Scarring Alopecia: Is it Safe and Effective?
Topical minoxidil and, more recently, low-dose oral minoxidil are often used to treat hair disorders. But are these treatments safe and effective for scarring alopecia? A scoping review published in the March issue of the Journal of Drugs in Dermatology sought to determine what research says about the use of these treatments for central centrifugal cicatricial alopecia, frontal fibrosing alopecia, …
Topical minoxidil and, more recently, low-dose oral minoxidil are often used to treat hair disorders. But are these treatments safe and effective for scarring alopecia? A scoping review published in the March issue of the Journal of Drugs in Dermatology sought to determine what research says about the use of these treatments for central centrifugal cicatricial alopecia, frontal fibrosing alopecia, … Continue reading "JDD Buzz Series | Minoxidil for Scarring Alopecia: Is it Safe and Effective?"
INTRODUCTION
Graham-Little-Piccardi-Lasseur Syndrome (GLPLS) is a rare clinical subtype of lichen planopilaris (LPP) that manifests as a triad of scarring alopecia of the scalp, nonscarring alopecia of the axillary and the pubic skin, and widespread lichenoid follicular papules.1 GLPLS more commonly affects women (male-to-female ratio ≃ 1:4), with the classic patient being a middle-aged Ca … 
A 55 year-old woman comes in for a rash in her mouth pictured below. Also on exam, you note a scarring alopecia of the scalp. From the below options, which other location should you examine for hair loss?
A. Eyebrows
B. Legs
C. Axilla
D. Arms
E. Eyelashes
To find out the correct answer and read the explanation, click here.
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This condition is associated with mutations in which of the following?
A. Peptidyl arginine deiminase, type III (PADI3)
B. Copper-transporting-P-type ATPase 7A (ATP7A)
C. Keratin 81 (K81)
D. ATP-dependent DNA helicase (ERCC2)
E. Keratin 86 (K86)
To find out the correct answer and read the explanation, click here.
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Unique characteristics of Central Centrifugal Cicatricial Alopecia (CCCA) range from hair breakage and thinning to follicular dropout and scarring to pinpoint papules within areas of new onset scarring.
Central centrifugal cicatricial alopecia (CCCA) is a progressive scarring alopecia affecting 3-6% of middle-aged, almost exclusively, Black women. CCCA classically presents as a patch of hai … 