Friday Pop Quiz 4/18/2025
A 2-week-old neonate has multiple blisters and erosions on the scalp, trunk, and extremities since birth. New lesions can be induced by mild friction. A biopsy is obtained from an induced blister and demonstrates cleavage at the dermal-epidermal junction and absent type VII collagen on immunofluorescence. What is the most likely genet …
A 2-week-old neonate has multiple blisters and erosions on the scalp, trunk, and extremities since birth. New lesions can be induced by mild friction. A biopsy is obtained from an induced blister and demonstrates cleavage at the dermal-epidermal junction and absent type VII collagen on immunofluorescence. What is the most likely genet … 
A 6-month old infant develops tense blisters on the distal extremities which develop on normal-appearing skin. He has a neurologic disease and has been immobilized for a long period of time. The blisters spontaneously heal within 1-2 weeks. You suspect a diagnosis of coma bullae. Which of the following is the key characteristic histologic feature that would assist you in making this diagnosis? … 