Sonidegib Therapeutic Cheat Sheet
Basal cell carcinoma (BCC) is the most common human cancer. When curative surgery and radiotherapy are contraindicated, systemic agents targeting the hedgehog signaling pathway are invaluable options for this subset of adult patients with locally advanced BCC (laBCC). Vismodegib and sonidegib are oral options with similar efficacy and side effect profiles. With the absence of head-to-head comparis …
Basal cell carcinoma (BCC) is the most common human cancer. When curative surgery and radiotherapy are contraindicated, systemic agents targeting the hedgehog signaling pathway are invaluable options for this subset of adult patients with locally advanced BCC (laBCC). Vismodegib and sonidegib are oral options with similar efficacy and side effect profiles. With the absence of head-to-head comparis … 
Verywell Health and several other media outlets are covering the issue of melanoma overdiagnosis in light of a recent study, which estimated more than 80,000 melanomas were overdiagnosed in white Americans in 2018 alone. Is melanoma overdiagnosis among white Americans a significant issue? What are the driving factors of overdiagnosis? What can dermatologists do better when diagnosing melanoma? … 
One of the latest TikTok trends has dermatologists concerned about the risks of pulmonary damage and allergic reactions. The “Lazy Girl” makeup trend involves applying self-tanner overnight to contour the face, according to FOX News. However, dermatologist Dr. Fayne Frey finds this trend disturbing, and dermatologist Dr. Mariano Busso cautions that results can vary.
Skin, hair and nail tren … 
Current field-directed treatments of actinic keratosis (AK), a pre-malignant condition, are often limited by severe local reactions and/or complex treatment. Tirbanibulin, a novel potent anti-proliferative synthetic agent that inhibits tubulin polymerization and Src kinase signalling, offers a convenient, safe, and effective field treatment of actinic keratosis. We continue our surgical Therapeut … 
JDD authors Mihir Shah MD, Jenna Wald MD, and C. William Hanke MD MPH present a case of a patient with eruptive squamous cell carcinomas following treatment with Fludarabine to highlight not only the risk of cSCC in CLL patients and the increased risk for atypical cutaneous malignancies after treatment with systemic therapies such as fludarabine, but also to discuss treatment options for this … 